Orange Campus was officially transferred to Charles Sturt University from the University of Sydney on 1 January 2005.
Originally the Orange Campus was home to the Orange Agricultural College, established in 1973 to offer courses principally related to the management of agricultural businesses.
The Orange Agricultural College was then linked with the University of New England (UNE) from 1990 to 1994, before becoming a part of the University of Sydney.
In 2000, the Orange Agricultural College was officially dissolved, while still remaining part of the University of Sydney.
The official opening of Orange Campus as a campus of Charles Sturt University took place on 8 September 2006.